Springside Infusion Blog

Announcements & Thought Leadership from Springside
Back to the Blog

VYEPTI for Migraine Prevention: A New Option for Fewer Migraine Days

An FDA-approved infusion therapy that helps reduce migraine days before they start

If you experience frequent migraines, you know they're much more than "just a headache." Migraines can disrupt work, family life, and everyday activities, leaving many people searching for better ways to prevent them.

For adults living with chronic or frequent migraines, VYEPTI (eptinezumab-jjmr) is an FDA-approved infusion therapy designed to help reduce the number of migraine days before they start.

At Springside Infusion, we work with your neurologist to provide a comfortable, safe environment for receiving VYEPTI infusions.


What Is VYEPTI?

VYEPTI is a prescription medication used to prevent migraines in adults. Unlike medications taken after a migraine begins, VYEPTI is designed to reduce how often migraines occur.

It belongs to a class of medications called CGRP (calcitonin gene-related peptide) inhibitors. CGRP is a protein involved in triggering migraine attacks. By blocking CGRP, VYEPTI helps prevent migraines before they start.


Who May Benefit from VYEPTI?

Your neurologist may recommend VYEPTI if you:

  • Experience frequent migraine attacks
  • Have chronic migraine (15 or more headache days per month, with at least 8 migraine days)
  • Have not responded well to other preventive medications
  • Prefer an infusion every three months rather than taking medication daily or monthly

Your physician will determine whether VYEPTI is appropriate based on your medical history and migraine pattern.


What to Expect During Your Infusion

One of the advantages of VYEPTI is that the infusion itself is relatively short.

During your appointment:

  • Your nurse will review your health history and current medications.
  • An IV will be placed in your arm.
  • The infusion is administered over approximately 30 minutes.
  • You'll be monitored during and after treatment to ensure you're feeling well.

Most patients can return to their normal daily activities shortly after their appointment.


How Often Is Treatment Given?

VYEPTI is administered once every three months, making it one of the least frequent preventive migraine treatments available.

Many patients appreciate the convenience of quarterly appointments rather than remembering daily pills or monthly injections.


Are There Side Effects?

Most patients tolerate VYEPTI well.

Possible side effects may include:

  • Nasal congestion
  • Sore throat
  • Mild infusion-related reactions
  • Allergic reactions (rare)

Your infusion nurse will monitor you throughout your treatment and answer any questions you may have.


Why Receive VYEPTI at an Outpatient Infusion Center?

Choosing an outpatient infusion center offers several advantages:

  • Comfortable, relaxing treatment environment
  • Experienced infusion nurses
  • Convenient scheduling
  • Close communication with your neurologist
  • Personalized care during every visit

Our team also works with your physician and insurance provider to coordinate benefits and prior authorizations before treatment begins whenever possible.


Helping You Get Back to Living

Migraines shouldn't control your schedule.

If your neurologist has recommended VYEPTI, Springside Infusion is here to make your treatment experience as comfortable and convenient as possible. Our experienced team is committed to providing exceptional care so you can focus on spending more time doing the things you enjoy and less time managing migraines.


Frequently Asked Questions

How quickly does VYEPTI begin working?

Some patients notice improvement as early as the first day after treatment, while others experience gradual improvement over the following weeks. Results vary from person to person.

How long does the infusion take?

The medication is infused over approximately 30 minutes, although your total appointment may be longer to allow for check-in, preparation, and observation.

Can I drive myself home after my infusion?

Most patients are able to drive themselves home and resume their normal daily activities unless instructed otherwise by their physician.

Will my insurance cover VYEPTI?

Many insurance plans cover VYEPTI when medically appropriate. Our team works closely with your physician and insurance provider to verify benefits and obtain any required prior authorizations before treatment.